He Bailin, Wang Yingyun, Li Tongying, Wu Xiuying (General Hospital of PLA)
Lu Zhongding, Ma Kuirong, Sun Yanzhu (Department of Endocrinology, Institute of Zoology, Academia Sinica)
Aspirin as an inhibitor to the biosynthesis of prostaglandin diminishes the sensitivity of pain receptor and may have some influence upon acupuncture analgesia. Experiments on normal subjects showed that ingestion of 1.5g of aspirin alone produced no significant changes in pain and pain tolerance thresholds tested 1-2 hours after administration of the drug. But intake of the same amount of aspirin followed by 30 minutes of electro-acupuncture caused marked elevation of pain and pain tolerance thresholds, especially the latter. The analgesia persisted even 30 minutes after removal of needles. This suggests that aspirin alone does not raise the pain threshold of the human skin but it enhances acupuncture analgesia. We observed the effect of aspirin on acupuncture analgesia for tubal ligation, high ligation of saphenous vein, thyroid surgery, repair of inguinal hernia and appendectomy in a total of 740 cases.
Analgesia was better in the aspirin group with higher percentage of grade I and II. Whether or not the prostaglandin is involved in the acupuncture analgasia needs further investigation.
Lu Zhongding, Ma Kuirong, Sun Yanzhu (Department of Endocrinology, Institute of Zoology, Academia Sinica)
Aspirin as an inhibitor to the biosynthesis of prostaglandin diminishes the sensitivity of pain receptor and may have some influence upon acupuncture analgesia. Experiments on normal subjects showed that ingestion of 1.5g of aspirin alone produced no significant changes in pain and pain tolerance thresholds tested 1-2 hours after administration of the drug. But intake of the same amount of aspirin followed by 30 minutes of electro-acupuncture caused marked elevation of pain and pain tolerance thresholds, especially the latter. The analgesia persisted even 30 minutes after removal of needles. This suggests that aspirin alone does not raise the pain threshold of the human skin but it enhances acupuncture analgesia. We observed the effect of aspirin on acupuncture analgesia for tubal ligation, high ligation of saphenous vein, thyroid surgery, repair of inguinal hernia and appendectomy in a total of 740 cases.
Analgesia was better in the aspirin group with higher percentage of grade I and II. Whether or not the prostaglandin is involved in the acupuncture analgasia needs further investigation.
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