Thursday, July 24, 2008

The Observation On Adrenal Cortex Function In Operation Under Acupuncture Anaesthesia And Drug Anaesthesia

Jin Jingshan, et al. (Research Laboratory of Biochemistry, Institute of Traditional Chinese Medicine, Beijing)

Li Weifan, et al. (Department of Surgery, Beijing Hospital of Traditional Chinese Medicine)

Under acupuncture anaesthesia or drug anesthesia adrenal cortex function has been compared in thyromadectomy and inguinal herniorrhaphy. After being admitted to the hospital, two specimens of 24-hour urine from the patient were collected  before operation as contrast, and on the day of the operation and after operation, 5-7 specimens of 24-hour urine were continuously collected for the determination of 17-hydroxycorticosteroid, 17-ketosteriod and aldosterone contents in urine respectively.


1. The change of aldosterone activity in 23 patients under acupuncture anaesthesia and 10 cases with drug anaesthesia was observed, which was not different between them before operation, but was increased during operation. However, the change with drug anaesthesia was not significant (>0.05), while that under acupuncture anaesthesia was significant (P<0.05). Aldosterone activity in the group of drug anaesthesia increased to the maximum value in the first day after operation, began to decrease in the second day after operation, continuously decreased in the third day, until near to level before operation in the fourth day after operation. Aldosterone activity in the group of acupuncture anaesthesia continuously increased in the first day after operation, up to the maximum value in the second day began to decrease in the third day, and near the level before operation in the fourth day after operation.


2. The change of 17-hydroxycorticosteroid in 28 patients under acupuncture anaesthesia and 10 cases with drug anaesthesia was observed, which was obviously increased in acupuncture anaesthesia cases on the first day after operation (P<0.05), while that with drug anaesthesia was not significant (P>0.05).

3. At the same time, the change of 17-ketosteroid in 29 patients under acupuncture anaesthesia and 10 cases with drug anaesthesia was observed. The result showed no statistical significance and the change was not regular.


The above results indicated that in the course of operation under acupuncture anaesthesia, the content of aldosterone and 17-hydroxyconticosteroid was higher than that in drug anaesthesia and it was statistically significant.

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